We work and thrive in innovation hubs in the U.S. and Australia

Our founders had an early ambition to make Protagonist a global company, attracting the best and brightest from every region to its offices in Silicon Valley and Brisbane.

Bay Area

Newark, California

Our presence in the Bay Area launched with a small office in Redwood City in 2009, hosting the handful of employees who built the company’s U.S. presence—our CEO, Dinesh Patel, among them. Today, Protagonist is proudly headquartered at the Pacific Research Center in Newark, California, home to some of the region’s most vibrant biotechnology companies. Over decades, members of Protagonist’s management team have played important roles in the growth of biotech in the region. Their pioneering spirit carries through to our own company’s growth, attributable in part to the extraordinary innovation ecosystem that surrounds us in California.

The region’s future remains bright, consistently ranking within the top-tier of the world’s biotechnology clusters. Explore open positions in our Newark, California headquarters here.

Corporate Headquarters Protagonist Therapeutics Inc.

7707 Gateway Boulevard, Suite 140 Newark, CA 94560-1160 USA

+1 510 474 0170

Top talent from far and wide

The most striking advantage our two locations confer lies in the diversity of talent surrounding both. Newark and Brisbane each host truly international communities. The composition of our teams reflects this diversity, in turn enhancing every aspect of our workplace culture and performance.

Since 2020, we have seamlessly integrated remote workers into our organizational infrastructure. In the coming months and years, we look forward to adding offices and talent in new cities, under flexible work arrangements, in step with our vision for continued expansion over time.


Brisbane, Australia

Protagonist’s discovery platform was first conceived in the world-class research labs of the University of Queensland (UQ)—a fixture of Brisbane’s dynamic and growing life sciences community. There, our scientific founder, Mark Smythe, PhD, applied a deep understanding of combinatorial chemistry and molecular design to the development of tools for the discovery of novel drug compounds. Today, in addition to his leadership at Protagonist, Mark remains a Principal Research Fellow and Group Leader at UQ’s Institute for Molecular Biosciences. Meanwhile, our Brisbane office has become a fixture, in its own right, of the area’s rich innovation ecosystem.

The advantages of our Brisbane office go well beyond the 280 days of sunshine enjoyed there per year. Today, our R&D scientists in Brisbane work hand-in-glove with our U.S. team to keep projects moving forward around the clock. A sought-after destination, Brisbane attracts top talent from across Australia, southeast Asia, and beyond.

Protagonist Pty Ltd

306 Carmody Road St Lucia, Brisbane Qld 4072 Australia

+61 (7) 3346 2975
+61 (7) 3346 2379

Join our team

We are motivated to make a difference for all those who can someday benefit from the therapies we discover and develop. Protagonist bring together leaders in the life sciences who share this sense of purpose. We invite you to connect with us and explore opportunities to participate in this great work. Find open positions at our company here.

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